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Grand Strand Medical Center
South Strand Medical Center

Cardiovascular Disease: General Signs and Symptoms

Doctors can usually diagnose cardiovascular disease (CVD) by observing symptoms and risk factors from the medical history and signs from the physical exam. Certain symptoms tend to be more or less common in certain conditions. For example, shortness of breath often characterizes heart failure, whereas angina is often a sign of coronary artery disease (CAD). Keep in mind that not all signs and symptoms are present for all types of CVD. Some are present only in a few conditions, others are in several different conditions, and all can be indicative of many things other than CVD. And sometimes, there are no symptoms at all until the disease reaches a late stage.

Major symptoms suggestive of cardiovascular conditions include:

  • Angina—The specific type and location of chest pain can tell a lot about its cause. For example, a tightness or squeezing sensation in the chest often indicates angina or heart attack. On the other hand, chest pain that gets worse when lying down and doesn’t worsen with exertion is more likely to be a symptom of pericarditis, an inflammation of the sac surrounding the heart.
  • Leg PainPeripheral artery disease (PAD), often leads to cramping and fatigue in the legs with exertion.
  • Shortness of breath—Fluid backing up into the lungs from a failing heart leads to shortness of breath, which is often made worse by laying down. While shortness of breath is common to many types of cardiovascular conditions, it is no by no means limited to CVD. The symptom is very common, for example, with lung diseases.
    Fluid in the Lungs
    Pulmonary Edema
    © 2011 Nucleus Medical Media, Inc.
  • Fatigue—Fatigue is another common symptom of CVD, presumably caused by insufficient blood flow to the muscles along with the decreased availability of oxygen due to fluid in the lungs.
  • Palpitations—A heart that is beating at an unusual force, rate, or rhythm, could just be an indication of anxiety or too much caffeine. However, abnormal heartbeats—especially if they occur in conjunction with other symptoms like fatigue or fainting—could hint at a more serious underlying condition, such as an arrhythmia.
  • Lightheadedness and Fainting—Insufficient blood flow to the brain can cause lightheadedness or fainting. This may be due to abnormal heart rate or rhythm, or to insufficient cardiac output. Of course, fainting may have many other causes ranging from anxiety to seizure disorders, and in most individuals is not due to CVD.

Signs suggestive of cardiovascular conditions include:

  • Pale, clammy appearance
  • Cyanosis (blue tinge to the skin), particularly in the extremities
  • Rapid or shallow breathing
  • Rapid and/or irregular heart rate
  • High or low blood pressure
  • Swollen veins in the neck
  • Swelling in the feet and ankles
  • Abnormalities in the retina (back of the eye)
  • Enlarged heart—cardiomyopathy (measured by placing hand on chest)
  • Extra or abnormal heart sounds (via stethoscope)
  • Fluid in the lungs (via stethoscope)
  • Abnormal sounds of arterial blood flow throughout the body (via stethoscope)
  • Pulsating abdominal mass—aortic aneurysm
  • Cool extremities
  • Reduced or absent pulses in the extremities

Revision Information

  • Cardiovascular examination. Merck Manual Professional Version website. Available at: Updated June 2013. Accessed September 23, 2015.

  • Coronary artery disease (CAD). EBSCO DynaMed website. Available at: Updated July 9, 2015. Accessed September 23, 2015.

  • Heart failure with reduced ejection fraction. EBSCO DynaMed website. Available at: Updated July 9, 2015. Accessed September 23, 2015.

  • What are the signs and symptoms of coronary heart disease? National Heart, Lung, and Blood Institute website. Available at: Updated September 29, 2014. Accessed September 23, 2015.